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Malaria in the Americas: We Have Not Won the Fight Just Yet
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Read part 2 here

In the last decade, the nations of the Americas have experienced a 53 percent drop in malaria cases with a 57 percent drop in malaria-related deaths. Current trends suggest that previously endemic countries including Argentina, Mexico, El Salvador, and Paraguay, have great potential for malaria elimination in the coming years. However, it is not time to start celebrating just yet.

Malaria-Mosquito-for-webTransmission
Malaria is caused by parasites of the genus Plasmodium with four species that affect humans including falciparum, ovale, malarae, and P. vivax, the most common strain of the disease in the Americas. Haiti and the Dominican Republic, which make up the island of Hispaniola, are the only exception with 100 percent of cases due to P. falciparum.

While malaria caused by P. falciparum often receives more attention due to its high mortality rates in Sub Saharan Africa, malaria caused by P. vivax deserves equal attention. It is highly prevalent throughout the world, particularly in the Americas.

Regional Challenges
The overall reduction of malaria cases in the Americas is a significant public health accomplishment; however malaria continues to be a major concern in some regions. Eighty-nine percent of malaria cases are concentrated in the Amazon. In 2007, Brazil reported the highest number of malaria cases, which make up 56 percent of all cases in the Americas. 

Some communities have reported a disproportionate incidence of malaria. In 2008, the municipality of Anajas in Brazil reported 452 cases per 1,000 inhabitants. Additionally, municipalities in Bolivia, Brazil, Colombia, Honduras, Peru, Suriname, and Venezuela reported incidences equal to or greater than 100 per 1,000 inhabitants.

Communities with alarming disease incidences generally share the following attributes:

• limited access to healthcare
• minimal institutional development
• extreme poverty
• lack of environmental sustainability
• the deterioration of natural resources

In some areas of Colombia, for example, malaria is related to illegal crop cultivation and the forced displacement of people.

In 2008, the United States and Canada, which are considered non endemic countries, reported 1,321 malaria cases with nearly all cases originating abroad.

Hispaniola is the Caribbean’s only malaria-endemic area with cases on the rise in Haiti. In 2008, Haiti reported a 57 percent increase in malaria cases from 2007, making it the country with the fourth highest disease burden in the Americas. Meanwhile, the Dominican Republic reported a 32 percent decrease; however, most cases remain centralized near areas bordering Haiti.

malaria_foggingLessons Learned
Malaria eradication has garnered much-needed attention in the last decade; however this is not the first attempt. In 1959, the World Health Organization (WHO) embarked on its Global Malaria Eradication Campaign, which relied primarily on the spraying of the dichloro-diphenyl-trichloroethane (DDT) insecticide. Although the global program achieved long-term eradication in many developed parts of the world such as Australia and most of Europe, the Americas experienced a re-emergence of malaria cases to levels higher than prior to the campaign.

In 1969, the WHO publically recognized that the campaign was not adequately equipped to fully carry out its objectives. While vector resistance to DDT contributed to incidence re-emergence in some areas, the main issue affecting the program was that individual countries did not have ample resources to sustain malaria control

The method of eradication relied on a “one-size fits all” approach and did not take into account varying social and epidemiological characteristics of each country. The use of a standardized approach thus made program implementation difficult on the community level as implementation was the responsibility of individual countries. This led to inconsistent DDT use and subsequently resulted in vector resistance. This coupled with the fact that many countries experienced a rapid decrease in incidence levels also led to a decline in political and financial commitment once malaria control in some targeted areas had begun to take effect. Eventually, funding for the campaign decreased and malaria eradication remained a low priority for many years, allowing it to reemerge and spread unchecked.

Shortly following the end of the eradication campaign, DDT use came under global scrutiny. Rachel Carson’s Silent Spring, widely credited with launching the environmental movement, outlined its potential environmental harm. The DDT scare prompted a ban of the insecticide. Initially, it was prohibited for use in agriculture; however in 1972 the U.S. led a global ban of DDT for all uses.

The ban subsequently influenced malaria reduction initiatives, which in recent years leading up to current global efforts relied mainly on diagnosis and treatment rather than vector control and prevention. Although other insecticides have been used, none have proven to be as effective and are more costly.

In 2006 the WHO reversed its 30-year policy to fully endorse the worldwide use of DDT for malaria control, prompting other donor agencies to follow suit.

Today’s malaria campaigns have adopted a more targeted and comprehensive approach by addressing the varying determinants of malaria transmission.  At such a time of great interest in malaria eradication, current national and international campaigns have great potential for success and continued commitment.

Malaria Champions of the Americas
Despite the many obstacles, progress is being made to conquer malaria in the Americas. Every year, on November 6th, Malaria Day in the Americas is celebrated. To recognize the outstanding work being done in the region to create a future free from the threat of malaria, PAHEF, PAHO, and the George Washington University Center for Global Health recognize the Malaria Champions of the Americas. These champions have performed outstanding works against difficult odds.

Read part 2 here

Read more about the 2010 Malaria Champions of the Americas and their accomplishments.

Sources:

1. http://news.bbc.co.uk/2/hi/science/nature/5350068.stm
2. http://cei.org/PDFs/malaria.pdf
3. http://new.paho.org/hq/index.php?option=com_content&task=view&id=2459&Itemid=2000
4. http://www.sciencemag.org/cgi/content/full/329/5992/618
5. http://www.usnews.com/science/articles/2010/08/06/understanding-the-malaria-causing-parasite.html
6. http://www.rollbackmalaria.org/gmap/3-3.html
7. http://wwwcgi.rand.org/labor/seminars/adp/pdfs/2008_bleakley.pdf

 
A Sample of Recent PAHEF Projects in the Region
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